The lab of Thomas Juffmann, together with researchers from the University of Siegen, has developed a new technique that combines electron microscopy and laser technology to enable programmable, arbitrary shaping of electron beams. It can potentially be used for optimizing electron optics and for adaptive electron microscopy, with applications in structural biology and materials science. The technology maximizes sensitivity while minimizing beam-induced damage. The results are published in Physics Review X.
How animals are able to interpret natural light sources to adjust their physiology and behavior is poorly understood. The labs of Kristin Tessmar-Raible (Max Perutz Labs Vienna, Alfred Wegener Institut, University of Oldenburg) and Eva Wolf (Johannes Gutenberg University and Institute of Molecular Biology Mainz) have now revealed that a molecule called L-cryptochrome (L-Cry) has the biochemical properties to discriminate between different moon phases, as well as between sun- and moonlight. Their findings, published in Nature Communications, show that L-Cry can interpret moonlight to entrain the monthly (circalunar) clock of a marine worm to control sexual maturation and reproduction.
Congratulations to Stephanie Ellis who has received the 2022 Vallee Scholar Award from the Vallee Foundation. The career development grant aims to support outstanding junior faculty carrying out basic biomedical research and will help to fund Stephanie’s work on cell competition over the next four years.
From September 15 - 17, 2022 group leader Jörg Menche and his team hosted “The Shape of Things to Come”, a 3-day mixed-reality exhibition. At various locations across the Vienna BioCenter, scientists and artists presented their ideas of how they picture our future environment in augmented and virtual reality.
Stem cells intrinsically express genes normally associated with the innate immune system, but in the absence of external stimuli such as viral infections. In new work published in EMBO Reports, the lab of Christa Bücker has discovered that expression of a key gene of the innate immune response, Irf1, is controlled by the gene regulatory network that regulates the transition from naïve to formative pluripotency during embryonic development. Their findings suggest that antiviral defense is upregulated to transiently protect the embryo from viral infections during a critical timepoint in development.
Congratulations to Max Perutz Labs faculty member Manuela Baccarini, who has been elected new Vice-Rector for Research and International Affairs of the University of Vienna. She will be part of the rectorate team led by rector Sebastian Schütze that will start its tenure in October 2022.
The Max Perutz Labs are embedded in the Vienna BioCenter, providing access to outstanding core facilities shared by all members of the campus in addition to facilities unique to our institute.
With a strong molecular focus and a diversity of model organisms, we aim to bridge basic research with biomedicine.
To honour an extraordinary teacher and scientist, the Max Perutz Labs were named after Max Ferdinand Perutz, who, together with John C. Kendrew, was awarded the 1962 Nobel Prize in Chemistry for his studies on the structure of globular proteins ...
The Max Perutz Labs are an international research institution in which people from all over the world come together to conduct scientific research. The Perutz recognizes and respects diversity as an important asset in establishing an inclusive and productive work environment for all parties, may it be students, scientists or support staff. We are committed to a workplace that values diversity and internationality, where people from various backgrounds and perspectives feel welcome and are supported in a safe environment. Whether it be race, ethnicity, national origin, religion, social background, age, gender, sexual orientation or disability - we aim to establish a community in which everyone feels included and is treated fairly and respectfully. We believe that there is always room for improvement and that a statement is worth nothing without action, but we continuously strive to do better and encourage every individual to play an active role in creating this environment.
The Max Perutz Labs seek to educate students to think critically and analytically, challenge them to set ambitious goals, and instill in them both broad horizons and deep understanding. In doing so, we aspire to furnish them with the necessary knowledge and skills to push forward the frontiers of 21st century biomedical science.